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Understanding how acute myeloid leukaemia and the bone marrow shape one another — and how to break the cycle

Based at Brighton and Sussex Medical School, we combine molecular biology with in vitro and in vivo models of the marrow niche to find new therapeutic targets in AML.

Led by Dr Fabio Simoes, Assistant Professor in Cancer Research

Brighton and Sussex Medical School · Falmer, Brighton

What we do

Three connected research themes

AML biology

Dissecting the pathological mechanisms that drive acute myeloid leukaemia and sustain disease after treatment.

Bone marrow

Mapping how the marrow niche protects leukaemia cells and drives drug resistance.

New drug targets

Identifying and testing targets

AML

Focus

Brighton

Location

Latest news…

The team

Principal Investigator

PhD Student

Interested in joining the lab?

We welcome enquiries from prospective PhD, MSc, and undergraduate students, and from potential collaborators in haematology and cancer biology.